If a malfunction of the lymphatic drainage due to blockage of the lymphatic vessels leads to lymphedema , fluid accumulation in the interstitium (intercellular space). This can also occur when part of a tumor resection, the adjacent lymph were removed. Another cause is the predominantly occurring in tropical regions elephantiasis , in which insect-borne parasitic worms ( filaria ) impede the flow of lymph. Affected are usually the legs and external genitals.
Caused by bacterial infection of the lymph channels is called lymphangitis referred to the inflammation of the lymph nodes as lymphadenitis . cancer cells can be from the primary tumor spread via the lymphatic vessels in the body. One then speaks of lymphatic metastasis . Metastases that form in the lymph nodes, called lymph node metastases .
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